Halobetasol Propionate

CAS No. 66852-54-8

Halobetasol Propionate ( BMY-30056; CGP-14458; Ulobetasol propionate )

Catalog No. M18974 CAS No. 66852-54-8

Halobetasol Propionate is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 36 In Stock
50MG 67 In Stock
100MG 104 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Halobetasol Propionate
  • Note
    Research use only, not for human use.
  • Brief Description
    Halobetasol Propionate is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities.
  • Description
    Halobetasol Propionate is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses across cell membranes to interact with cytoplasmic corticosteroid receptors located in both the dermal and intradermal cells, thereby activating gene expression of anti-inflammatory proteins mediated via corticosteroid receptor response element. Specifically, this agent induces phospholipase A2 inhibitory proteins, which inhibit the release of arachidonic acid, thereby inhibiting the biosynthesis of potent mediators of inflammation, such as prostaglandins and leukotrienes. As a result, halobetasol reduces edema, erythema, and pruritus through its cutaneous effects on vascular dilation and permeability.
  • Synonyms
    BMY-30056; CGP-14458; Ulobetasol propionate
  • Pathway
    GPCR/G Protein
  • Target
    Histamine Receptor
  • Recptor
    PLA2
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    66852-54-8
  • Formula Weight
    484.96
  • Molecular Formula
    C25H31ClF2O5
  • Purity
    98%
  • Solubility
    DMSO : ≥ 35 mg/mL; 72.17 mM
  • SMILES
    C(=O)(CC)O[C@@]1([C@H](C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@]12C)O)F)C)F)C)C(=O)CCl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Mohandas S, et al. Indian J Dermatol Venereol Leprol, 2009, 75(2), 186-187.
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