Halobetasol Propionate
CAS No. 66852-54-8
Halobetasol Propionate ( BMY-30056; CGP-14458; Ulobetasol propionate )
Catalog No. M18974 CAS No. 66852-54-8
Halobetasol Propionate is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
10MG | 36 | In Stock |
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50MG | 67 | In Stock |
|
100MG | 104 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameHalobetasol Propionate
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NoteResearch use only, not for human use.
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Brief DescriptionHalobetasol Propionate is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities.
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DescriptionHalobetasol Propionate is the propionate salt form of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities. Halobetasol, a topical steroid, diffuses across cell membranes to interact with cytoplasmic corticosteroid receptors located in both the dermal and intradermal cells, thereby activating gene expression of anti-inflammatory proteins mediated via corticosteroid receptor response element. Specifically, this agent induces phospholipase A2 inhibitory proteins, which inhibit the release of arachidonic acid, thereby inhibiting the biosynthesis of potent mediators of inflammation, such as prostaglandins and leukotrienes. As a result, halobetasol reduces edema, erythema, and pruritus through its cutaneous effects on vascular dilation and permeability.
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SynonymsBMY-30056; CGP-14458; Ulobetasol propionate
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PathwayGPCR/G Protein
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TargetHistamine Receptor
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RecptorPLA2
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number66852-54-8
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Formula Weight484.96
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Molecular FormulaC25H31ClF2O5
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Purity98%
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SolubilityDMSO : ≥ 35 mg/mL; 72.17 mM
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SMILESC(=O)(CC)O[C@@]1([C@H](C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@]12C)O)F)C)F)C)C(=O)CCl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mohandas S, et al. Indian J Dermatol Venereol Leprol, 2009, 75(2), 186-187.
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